Comparative secretome analysis of four isogenic Bacillus clausii probiotic strains
نویسندگان
چکیده
منابع مشابه
Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities.
The clinical benefits observed with probiotic use are mainly attributed to the antimicrobial substances produced by probiotic strains and to their immunomodulatory effects. Currently, the best-documented probiotic bacteria used in human therapy are lactic acid bacteria. In contrast, studies aiming to characterize the mechanisms responsible for the probiotic beneficial effects of Bacillus are ra...
متن کاملCharacterization of a new erm-related macrolide resistance gene present in probiotic strains of Bacillus clausii.
The mechanism of resistance to macrolides, lincosamides, and streptogramins B was studied in four Bacillus clausii strains that are mixed in a probiotic administered to humans for prevention of gastrointestinal side effects due to oral antibiotic chemotherapy and in three reference strains of B. clausii, DSM8716, ATCC 21536, and ATCC 21537. An 846-bp gene called erm(34), which is related to the...
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Probiotics are vital bacteria that colonize the intestine and modify its microflora with benefits for the host. Very few members of the Bacillus group are recognized as safe for use and hence only a few strains are available as commercial preparations for application in humans and animals. Acute and subacute studies in rats were conducted to establish safety of Bacillus clausii (B. clausii) UBB...
متن کاملThe respiratory chains of four strains of the alkaliphilic Bacillus clausii
A comparative analysis of terminal respiratory enzymes has been performed on four strains of Bacillus clausii used for preparation of a European probiotic. These four strains originated most probably from a common ancestor through early selection of stable clones for industrial propagation. They exhibit a low level of intra-specific diversity and a high degree of genomic conservation, making th...
متن کاملAntibiotic Sensitivity of Bacillus clausii Strains in Commercial Preparation
Recently has been acknowledged the healthy use of Bacillus and related bacteria as probiotics. A mixture reported to contain four probiotic strains of Bacillus clausii is marketed as an OTC (Over The Counter) medicinal supplement for human use. Their poliantibiotic resistant property, useful for restoring the gut microbiota during antibiotic treatment, raises the question about the risk of resi...
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ژورنال
عنوان ژورنال: Proteome Science
سال: 2013
ISSN: 1477-5956
DOI: 10.1186/1477-5956-11-28